Tacrolimus
Tacrolimus
I-Anhydrous evela kwi-tacrolimus, i-macrolide esecaleni kwi-Streptomyces tsukubaensis.I-Tacrolimus ibophelela kwiprotheni ye-FKBP-12 kwaye yenza i-complex kunye neeprotheni ezixhomekeke kwi-calcium, ngaloo ndlela inqanda umsebenzi we-calcineurin phosphatase kwaye ibangele ukwehla kwemveliso ye-cytokine.
Ukusetyenziswa emva kokufakelwa kwelungu le-allogen ukunciphisa umsebenzi we-immune system yesigulane kwaye ngoko umngcipheko wokulahlwa kwelungu.Kwakhona isetyenziswe ekulungiseleleni izihloko kunyango lwe-atopic dermatitis enzima.
| Izinto | Iinkcukacha | Iziphumo |
| Imbonakalo | Umgubo omhlophe wekristale | Iyahambelana |
|
Ukuchongwa | Ixesha lokugcinwa kwencopho enkulu yoLungiselelo lwe-Assay luhambelana naleyo yechromatogram yoLungiso loMgangatho olufunyenwe njengoko kuchaziwe kwi-Assay. |
Iyahambelana |
| [α] D23,.kwiklorofomu | -75.0～ - 90.0º | -84.0º |
| Uluhlu lokunyibilika | 122～129℃ | 125～128.0℃ |
| Amanzi | ≤3.0% | 1.9% |
| Iintsimbi ezinzima | ≤10ppm | Iyahambelana |
| Intsalela ekutshisweni | ≤0.1% | Iyahambelana |
| Izinto ezinxulumeneyo | Ukungcola okupheleleyo≤2.0% | 0.5% |
| Isivavanyi | ≥98.0% | 98.6% |
| Izinto | Iinkcukacha | Iziphumo |
| Imbonakalo | Umgubo omhlophe wekristale | Iyahambelana |
|
Ukuchongwa | Ixesha lokugcinwa kwencopho enkulu yoLungiselelo lwe-Assay luhambelana naleyo yechromatogram yoLungiso loMgangatho olufunyenwe njengoko kuchaziwe kwi-Assay. |
Iyahambelana |
| [α]D23,.kwiklorofomu | -75.0º～ - 90.0º | -84.0º |
| Uluhlu lokunyibilika | 122～129℃ | 125～128.0℃ |
| Amanzi | ≤3.0% | 1.9% |
| Iintsimbi ezinzima | ≤10ppm | Iyahambelana |
| Intsalela ekutshisweni | ≤0.1% | Iyahambelana |
| Izinto ezinxulumeneyo | Ubumdaka bubonke ≤2.0% | 0.5% |
| Isivavanyi | ≥98.0% | 98.6% |
Ugcino: kwindawo eyomileyo, epholileyo, kunye nendawo enomthunzi enepakethe yokuqala, thintela ukufuma, gcina kwiqondo lokushisa.
Beka ubomi kwishelufa: iinyanga ezingama-48
Iphakheji:in25kg/ibhegi
ukuhanjiswa: khawuleza
1. Ithini imiqathango yakho yentlawulo?
T/T okanye L/C.
2. Lithini ixesha lakho lokuhambisa?
Ngokuqhelekileyo siya kulungelelanisa ukuthunyelwa kwiintsuku ze-7 -15.
3. Kuthekani ngokupakisha?
Ngokuqhelekileyo sibonelela ngokupakisha njenge-25 kg / ibhegi okanye ibhokisi.Ewe, ukuba uneemfuno ezizodwa kubo, siya kwenza ngokutsho kwakho.
4. Kuthekani malunga nokuba semthethweni kweemveliso?
Ngokweemveliso oziyaleleyo.
5. Ngawaphi amaxwebhu owabonelelayo?
Ngokuqhelekileyo, sinikezela nge-invoyisi yezoRhwebo, uLuhlu lokuPakisha, iBhili yokulayisha, i-COA, isatifikethi seMpilo kunye nesatifikethi seMvelaphi.Ukuba iimarike zakho zineemfuno ezizodwa, sazise.
6. Yintoni izibuko lokulayisha?
Ngokuqhelekileyo yiShanghai, iQingdao okanye iTianjin.
