Tacrolimus
Tacrolimus
Anhydrous ka tacrolimus, macrolide ka go'doon Streptomyces tsukubaensis.Tacrolimus waxay ku xidhan tahay borotiinka FKBP-12 waxayna samaysaa iskudhaf leh borotiinada calcium-ku-tiirsan, taas oo ka hortagaysa dhaqdhaqaaqa fosfatase calcineurin waxayna keentay hoos u dhaca wax soo saarka cytokine.
Isticmaalka ka dib wareejinta xubnaha allogenic si loo yareeyo waxqabadka nidaamka difaaca bukaanka iyo markaa khatarta diidmada xubnaha.Waxa kale oo loo isticmaalay diyaarinta jirka la mariyo ee daaweynta dermatitis daran ee atopic.
| Walxaha | Tilmaamaha | Natiijooyinka |
| Muuqashada | Budada crystalline cad | waafaqsan |
|
Aqoonsiga | Wakhtiga haynta ee ugu sarraysa ee diyaarinta Assay waxay u dhigantaa tan chromatogram-ka diyaarinta caadiga ah ee la helay sida lagu faray Assay |
waafaqsan |
| [α] D23,.in chloroform | -75.0º～ - 90.0º | -84.0º |
| Kala duwanaansho dhalaalid | 122～129℃ | 125～128.0℃ |
| Biyo | ≤3.0% | 1.9% |
| Biraha culus | ≤10ppm | waafaqsan |
| Hadhaaga dabka | ≤0.1% | waafaqsan |
| Walxaha la xidhiidha | Wadarta wasakhda≤2.0% | 0.5% |
| Qiimayn | ≥98.0% | 98.6% |
| Walxaha | Tilmaamaha | Natiijooyinka |
| Muuqashada | Budada crystalline cad | waafaqsan |
|
Aqoonsiga | Wakhtiga haynta ee ugu sarraysa ee diyaarinta Assay waxay u dhigantaa tan chromatogram-ka diyaarinta caadiga ah ee la helay sida lagu faray Assay |
waafaqsan |
| [α]D23,.in chloroform | -75.0º～ - 90.0º | -84.0º |
| Kala duwanaansho dhalaalid | 122～129℃ | 125～128.0℃ |
| Biyo | ≤3.0% | 1.9% |
| Biraha culus | ≤10pm | waafaqsan |
| Hadhaaga dabka | ≤0.1% | waafaqsan |
| Walxaha la xidhiidha | Wadarta wasakhda ≤2.0% | 0.5% |
| Qiimayn | ≥98.0% | 98.6% |
Kaydinta: meel qalalan, qabow, iyo meel hadh leh oo leh baakad asalka ah, iska ilaali qoyaanka, ku kaydi heerkulka qolka.
Nolosha shelf: 48 bilood
Xidhmada: gudaha25kg/bac
gaarsiin: degdeg
1. Waa maxay shuruudaha lacag bixinta?
T/T ama L/C.
2. Waa maxay wakhtigaaga dhalmada?
Caadiyan waxaanu diyaarin doonaa shixnadda 7-15 maalmood gudahood.
3. Ka waran xirxirida?
Sida caadiga ah waxaan ku siin baakad sida 25 kg / bac ama kartoon.Dabcan, haddii aad leedahay shuruudo gaar ah iyaga, waxaanu ku siin doonaa sida aad tahay.
4. Sidee ku saabsan ansaxnimada alaabta?
Marka loo eego alaabta aad dalbatay.
5. Waa maxay dukumentiyada aad bixiso?
Caadiyan, waxaan bixinaa qaansheeg ganacsi, Liiska baakad, Bill of loading, COA , Shahaadada caafimaadka iyo shahaadada asalka.Haddii suuqyadaadu ay leeyihiin wax shuruudo gaar ah, na soo ogeysii.
6. Waa maxay dekedu?
Caadi ahaan waa Shanghai, Qingdao ama Tianjin.
